@article{Phillips:2014aa,
	abstract = {The purpose of this study was to investigate the influence of an energy drink (ED) on cycling performance and immune-related variables. Eleven trained male cyclists (33.4 $\pm$ 8.9 years; 81 $\pm$ 7.6 kg; maximal VO2, 52 $\pm$ 3.4 ml·kg(-1)·min(-1)) consumed 500 ml of (a) ED (2.0 g taurine, 1.2 g glucuronolactone, 160 mg caffeine, 56 g carbohydrate [CHO], and B vitamins), (b) cola matched for caffeine and CHO (CC), or (c) flavored placebo (PL: sparking water and flavoring) 50 minutes before racing in a randomized, crossover design. Performance was measured as time to complete (TTC) a 25-mile simulated road race. Blood was collected at baseline, 30 minutes after drink consumption, during exercise at miles 5 (M5), 15 (M15), and immediately (POEX) and 30 minutes (30minPO) after exercise. TTC was not different (p > 0.05) among trials (ED, 68.6 $\pm$ 2.7; CC, 68.9 $\pm$ 3.8; PL, 69.6 $\pm$ 3.8 minutes). Consumption of CC and ED elicited a mild hypoglycemia elicited a mild hypoglycemia during cycling. POEX interleukin-6 (IL-6) was greatest after ED, whereas CC IL-6 was greater than PL (10.2 $\pm$ 1.6, 6.7 $\pm$ 0.6, and 4.8 $\pm$ 0.7 pg·ml(-1), respectively; p < 0.001). Cycling increased leukocyte number in all conditions with ED leukocyte number greater than that of PL at M15 (9.8 $\pm$ 0.6, 8.5 $\pm$ 0.3 × 10(6) cells·mL(-1)). Energy drink induced an earlier recruitment of monocytes to the blood stream than CC. Mean fat oxidation was greater in PL compared with CC (0.43 $\pm$ 0.06 and 0.28 $\pm$ 0.04 g·min(-1); p = 0.033) but did not differ between ED (0.32 $\pm$ 0.06) and PL. Lactate was higher in ED compared with CC and PL at M5 and M15 (p = 0.003), but there was no significant influence of either ED or CC on performance. Carbohydrate and caffeine consumption before endurance cycling significantly increased the IL-6 release and leukocytosis, and the additional ingredients in ED seem to have further augmented these responses.},
	address = {Texas Christian University, Fort Worth, Texas.},
	author = {Phillips, Melody D and Rola, Kelyn S and Christensen, Kenneth V and Ross, Jacob W and Mitchell, Joel B},
	crdt = {2013/11/01 06:00},
	date = {2014 May},
	date-added = {2022-12-31 08:55:46 +0000},
	date-modified = {2023-01-08 11:42:04 +0000},
	dcom = {20150121},
	doi = {10.1519/JSC.0000000000000275},
	edat = {2013/11/01 06:00},
	issn = {1533-4287 (Electronic); 1064-8011 (Linking)},
	jid = {9415084},
	journal = {J Strength Cond Res},
	jt = {Journal of strength and conditioning research},
	keywords = {Energy Drinks},
	language = {eng},
	lid = {10.1519/JSC.0000000000000275 {$[$}doi{$]$}},
	lr = {20161018},
	mh = {Adult; Athletic Performance/*physiology; Bicycling/*physiology; Blood Glucose/metabolism; Caffeine/administration \& dosage; Carbohydrates/administration \& dosage; Carbonated Beverages; Cross-Over Studies; *Energy Drinks; Exercise Test; Humans; Interleukin-6/*blood; Lactic Acid/*blood; Leukocyte Count; Male; *Monocytes; Physical Endurance/drug effects/*physiology; Physical Exertion/drug effects},
	mhda = {2015/01/22 06:00},
	month = {May},
	number = {5},
	own = {NLM},
	pages = {1443--1453},
	phst = {2013/11/01 06:00 {$[$}entrez{$]$}; 2013/11/01 06:00 {$[$}pubmed{$]$}; 2015/01/22 06:00 {$[$}medline{$]$}},
	pl = {United States},
	pmid = {24172719},
	pst = {ppublish},
	pt = {Journal Article; Randomized Controlled Trial},
	rn = {0 (Blood Glucose); 0 (Carbohydrates); 0 (Interleukin-6); 33X04XA5AT (Lactic Acid); 3G6A5W338E (Caffeine)},
	sb = {IM},
	status = {MEDLINE},
	title = {Preexercise energy drink consumption does not improve endurance cycling performance but increases lactate, monocyte, and interleukin-6 response.},
	url = {http://nelsontavares.com/r/papers/Preexercise%20energy%20drink%20consumption%20does%20not%20improve%20endurance%20cycling%20performance%20but%20increases%20lactate%20monocyte%20and%20interleukin-6%20response.pdf},
	volume = {28},
	year = {2014},
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	bdsk-url-1 = {https://doi.org/10.1519/JSC.0000000000000275},
	bdsk-url-2 = {http://nelsontavares.com/r/papers/Preexercise%20energy%20drink%20consumption%20does%20not%20improve%20endurance%20cycling%20performance%20but%20increases%20lactate%20monocyte%20and%20interleukin-6%20response.pdf}}