by Jorge Vega and Juan Pablo Huidobro E
Abstract:
Creatine supplements may transitorily rise serum creatinine levels and mimic a kidney disease. If its use is associated with a high protein diet, the resulting increase in blood urea nitrogen will increase the confusion. Since clinical laboratories usually inform the estimated glomerular filtration rate based on serum creatinine, its elevation may lead to over diagnose a chronic renal failure, with the inherent personal and public health consequences. Creatine supplements are safe and do not cause renal disease. Reports of kidney damage associated with its use are scanty. However, creatine supplements should not be used in people with chronic renal disease or using potentially nephrotoxic medications.
Reference:
Effects of creatine supplementation on renal function. (Jorge Vega and Juan Pablo Huidobro E), In Rev Med Chil, volume 147, 2019.
Bibtex Entry:
@article{Vega:2019aa,
abstract = {Creatine supplements may transitorily rise serum creatinine levels and mimic a kidney disease. If its use is associated with a high protein diet, the resulting increase in blood urea nitrogen will increase the confusion. Since clinical laboratories usually inform the estimated glomerular filtration rate based on serum creatinine, its elevation may lead to over diagnose a chronic renal failure, with the inherent personal and public health consequences. Creatine supplements are safe and do not cause renal disease. Reports of kidney damage associated with its use are scanty. However, creatine supplements should not be used in people with chronic renal disease or using potentially nephrotoxic medications.},
address = {Secci{\'o}n de Nefrolog{\'\i}a, Servicio de Medicina, Hospital Naval Almirante Nef, Vi{\~n}a del Mar, Chile.; Secci{\'o}n de Nefrolog{\'\i}a, Servicio de Medicina, Hospital Naval Almirante Nef, Vi{\~n}a del Mar, Chile.},
author = {Vega, Jorge and Huidobro E, Juan Pablo},
crdt = {2019/12/21 06:00},
date = {2019 May},
date-added = {2023-01-16 20:50:12 +0000},
date-modified = {2023-01-19 17:39:16 +0000},
dcom = {20200122},
doi = {10.4067/S0034-98872019000500628},
edat = {2019/12/21 06:00},
issn = {0717-6163 (Electronic); 0034-9887 (Linking)},
jid = {0404312},
journal = {Rev Med Chil},
jt = {Revista medica de Chile},
keywords = {Creatine},
language = {spa},
lid = {S0034-98872019000500628 {$[$}pii{$]$}; 10.4067/S0034-98872019000500628 {$[$}doi{$]$}},
lr = {20200122},
mh = {Creatine/*adverse effects; Creatinine/blood; Dietary Supplements/*adverse effects; Humans; Kidney/*drug effects/*physiopathology; Kidney Diseases/*chemically induced/physiopathology; Risk Factors},
mhda = {2020/01/23 06:00},
month = {May},
number = {5},
own = {NLM},
pages = {628--633},
phst = {2018/11/06 00:00 {$[$}received{$]$}; 2019/04/22 00:00 {$[$}accepted{$]$}; 2019/12/21 06:00 {$[$}entrez{$]$}; 2019/12/21 06:00 {$[$}pubmed{$]$}; 2020/01/23 06:00 {$[$}medline{$]$}},
pii = {S0034-98872019000500628},
pl = {Chile},
pmid = {31859895},
pst = {ppublish},
pt = {Journal Article; Review},
rn = {AYI8EX34EU (Creatinine); MU72812GK0 (Creatine)},
sb = {IM},
status = {MEDLINE},
title = {Effects of creatine supplementation on renal function.},
tt = {Efectos en la funci{\'o}n renal de la suplementaci{\'o}n de creatina con fines deportivos.},
volume = {147},
year = {2019},
bdsk-url-1 = {https://doi.org/10.4067/S0034-98872019000500628}}