by Jérôme Salles, Christelle Guillet, Olivier Le Bacquer, Carmen Malnero-Fernandez, Christophe Giraudet, Véronique Patrac, Alexandre Berry, Philippe Denis, Corinne Pouyet, Marine Gueugneau, Yves Boirie, Heidi Jacobs and Stéphane Walrand
Abstract:
Plant proteins are attracting rising interest due to their pro-health benefits and environmental sustainability. However, little is known about the nutritional value of pea proteins when consumed by older people. Herein, we evaluated the digestibility and nutritional efficiency of pea proteins compared to casein and whey proteins in old rats. Thirty 20-month-old male Wistar rats were assigned to an isoproteic and isocaloric diet containing either casein (CAS), soluble milk protein (WHEY) or Pisane\texttrademark pea protein isolate for 16 weeks. The three proteins had a similar effect on nitrogen balance, true digestibility and net protein utilization in old rats, which means that different protein sources did not alter body composition, tissue weight, skeletal muscle protein synthesis or degradation. Muscle mitochondrial activity, inflammation status and insulin resistance were similar between the three groups. In conclusion, old rats used pea protein with the same efficiency as casein or whey proteins, due to its high digestibility and amino acid composition. Using these plant-based proteins could help older people diversify their protein sources and more easily achieve nutritional intake recommendations.
Reference:
Pea Proteins Have Anabolic Effects Comparable to Milk Proteins on Whole Body Protein Retention and Muscle Protein Metabolism in Old Rats. (Jérôme Salles, Christelle Guillet, Olivier Le Bacquer, Carmen Malnero-Fernandez, Christophe Giraudet, Véronique Patrac, Alexandre Berry, Philippe Denis, Corinne Pouyet, Marine Gueugneau, Yves Boirie, Heidi Jacobs and Stéphane Walrand), In Nutrients, volume 13, 2021.
Bibtex Entry:
@article{salles_pea_2021,
abstract = {Plant proteins are attracting rising interest due to their pro-health benefits and environmental sustainability. However, little is known about the nutritional value of pea proteins when consumed by older people. Herein, we evaluated the digestibility and nutritional efficiency of pea proteins compared to casein and whey proteins in old rats. Thirty 20-month-old male Wistar rats were assigned to an isoproteic and isocaloric diet containing either casein (CAS), soluble milk protein (WHEY) or Pisane{\texttrademark} pea protein isolate for 16 weeks. The three proteins had a similar effect on nitrogen balance, true digestibility and net protein utilization in old rats, which means that different protein sources did not alter body composition, tissue weight, skeletal muscle protein synthesis or degradation. Muscle mitochondrial activity, inflammation status and insulin resistance were similar between the three groups. In conclusion, old rats used pea protein with the same efficiency as casein or whey proteins, due to its high digestibility and amino acid composition. Using these plant-based proteins could help older people diversify their protein sources and more easily achieve nutritional intake recommendations.},
author = {Salles, J{\'e}r{\^o}me and Guillet, Christelle and Le Bacquer, Olivier and Malnero-Fernandez, Carmen and Giraudet, Christophe and Patrac, V{\'e}ronique and Berry, Alexandre and Denis, Philippe and Pouyet, Corinne and Gueugneau, Marine and Boirie, Yves and Jacobs, Heidi and Walrand, St{\'e}phane},
date-modified = {2023-01-16 13:08:58 +0000},
doi = {10.3390/nu13124234},
issn = {2072-6643},
journal = {Nutrients},
keywords = {Protein, Muscle},
language = {eng},
month = nov,
number = {12},
pmcid = {PMC8704096},
pmid = {34959786},
title = {Pea {Proteins} {Have} {Anabolic} {Effects} {Comparable} to {Milk} {Proteins} on {Whole} {Body} {Protein} {Retention} and {Muscle} {Protein} {Metabolism} in {Old} {Rats}.},
volume = {13},
year = {2021},
bdsk-url-1 = {https://doi.org/10.3390/nu13124234}}